The Anti-IgA antibody clone IS11-8E10 detects both subclasses of human IgA. IgA is present either as monomer or in a secreted form as a multimer of 2-4 molecules, connected by the J-chain and the so-called secretory component. Secreted IgA is transported across epithelial cells and secreted into the lumen of the respiratory and gastrointestinal tract.
原厂资料:
The Anti-IgA antibody clone IS11-8E10 detects both subclasses of human IgA. IgA is present either as monomer or in a secreted form as a multimer of 2-4 molecules, connected by the J-chain and the so-called secretory component. Secreted IgA is transported across epithelial cells and secreted into the lumen of the respiratory and gastrointestinal tract.