收藏本站
热门搜索: A3500  E1910  A1360  25200056  dmem  

LRRK2-GFP LYSATE 25 PMOL

 
包装: 25 PMOL
运保温度: Store at -80°C.
到货周期: 登录后查看
标准价: ¥客户可见
会员价: ¥客户可见
积分: 客户可见
 
登录之后可加入购物车购买,请您 
对比 收藏

运费与支付说明:

1.含干冰类产品有运费;

2. 必须现金付款或有信用额度的会员才可以直接发货,否则需要等待现金付款信息。

描述:

This product is a cellular lysate containing recombinant human full-length C-terminal GFP-tagged LRRK2 expressed in HEK293T cells via BacMam technology. LRRK2-GFP Lysate is intended for use in the LanthaScreen® Eu Kinase Binding Assay.

Using LRRK2-GFP Lysate with the LanthaScreen® System Lets You:

• Work with a more biologically relevant full-length LRRK2 protein
• Obtain sensitive detection of kinase inhibitors
• Measure the right kinase

Examine LRRK2 Mutations with BacMam Reagents
LRRK2 is a multi-domain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in the LRRK2 gene have been associated with Parkinson's disease. The LRRK2-GFP Lysate utilizes a full length LRRK2 protein, offering users a more biologically relevant system than truncated proteins in which to assess LRRK2.

A Highly Specific Kinase Assay That is Not Dependent on Activity
Our kinase tracers are based on ATP-competitive kinase inhibitors, making them suitable for detection of any compounds that bind to the ATP site or to an allosteric site altering the conformation of the ATP site. Any signal resulting from the LanthaScreen® Eu Kinase Binding Assay is due to a specific interaction with the Eu-anti-GFP antibody bound to the kinase of interest, ensuring no signal will arise due to any other kinases or other enzymes present in a test sample. Unlike activity assays, the kinase binding assay can be performed with either active or non-activated kinase preparations, making it ideal for detection of Type II inhibitors.

Contact your sale representative for the larger 250 pmol—Catalog Number A14194 (not web-orderable)


注意事项:

Cellular lysate containing GFP-tagged Leucine-Rich Repeat Kinase 2, in 10 mM Tris, pH 7.4, 2.5 mM EDTA, 2.5 mM NaF, 75 mM NaCl, 0.5% NP-40, 10% glycerol and protease and phosphatase inhibitor cocktails.

Store at -80°C.


相关图片

本产品可用于的实验

购此产品的人还购买了
最近浏览产品

京ICP备15036693号-2    京公网安备11010802025653    版权所有:北京逸优科技有限公司       0.16

 纠 错